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PACKED RED BLOOD CELLS (PRBC’s) – Storage for 42 days at 4° C 

Packed Red Blood Cells (PRBC’s) are created by separating the blood cells from the plasma by centrifugation.  The red cells are supplied in a small amount of plasma to keep them in a liquid suspension (approximate hematocrit of 60% for PRBC's in Adsol  / Optisol).  PRBC’s are an ideal product when a patient is suffering from any form of anemia, or to improve oxygen-carrying capacity during or after vigorous fluid resuscitation. 

Key Benefits
bulletTyped for DEA 1.1 Negative or DEA 1.1 Positive
bulletUsed for any form of anemia

 

Whole Unit -  components produced from 450 ml of whole blood

Half Unit - components produced from 250 ml of whole blood

Call for Pricing - 1/2 units available on special request

Description Size

Type
PRBC's 1/2 unit DEA 1.1 Negative
PRBC's 1 unit DEA 1.1 Negative
PRBC's 1/2 unit DEA 1.1 Positive
PRBC's 1 unit DEA 1.1 Positive

How much blood should you transfuse? 

          Please see our Vet Resources page for more useful information to help you with your transfusions.

 

PRBC Dosage Calculator

Weight:
Desired PCV:
Patient PCV:
PRBC's PCV:
 
The amount of Packed Red Blood Cells (PRBC's)
needed to transfuse this patient is mLs

 

Pre-Transfusion Treatment

    Diphenhydramine  (Benadryl®):   1 mg/lb.     

 

Dosage Guidelines

PRBCs:  Packed red blood cells are dosed based using the following formula:

 

                             WT x 70 x (PCVdesired --- PCVpatient)

                   mL =                                                                 

                                                   PCVprbcs

                   

                    mL = mL to transfuse

                    WT = weight of patient (kg)

                    PCVdesired = Target PCV

                    PCVpatient = Patient’s current PCV

                    PCVprbcs = PCV of PRBCs*

 

*The PCV of the PRBCs can be measured directly, or assume PCV=60% (for Optisol® / Adsol®) or PCV=80% (for CPDA-1) as supplied by Sun States.  If you are rehydrating with saline, add 150 mL 0.9% NS and assume PCV=50%.

 

USE ONLY 0.9% NORMAL SALINE TO REHYDRATE PRBCs.  Dextrose or calcium-containing solutions (such as Lactated Ringer’s) may interfere with the anticoagulants solutions used to store blood products.

 

FFP, Plasma, Cryosupernatant: 

    6-12 mL/kg.  Severe deficits of immunoglobulin may require up to 20 mL/kg/dose over 2-4 hours.

 

Cryoprecipitate:  1-2 mL/kg.  Severe coagulopathies may require up to 5 mL/kg/dose over 1 hour.  In severe bleeding episodes repeat administration every 12 hours as needed to maintain hemostasis.

 

Administration: 

bullet

Start all infusions at a slow rate (10 mL/hour or less) and titrate upward after several minutes.  To minimize the risk of transfusion reactions, plan to infuse over a 2 – 4 hour timeframe.

bullet

If a transfusion reaction occurs, STOP THE TRANSFUSION.  Additional Benadryl®  or corticosteroids can be administered.  For mild reactions, the transfusion may be resumed at a slower rate once symptoms have subsided.

 

Disclaimer:

This page is provided for educational use only. Although every effort has been made to ensure reliability, Sun States: Blood Banks for Animals does not make any warranty, either expressed or implied regarding the performance of this calculator; nor shall they have any liability or responsibility with respect to any claim, loss or damage caused or alleged to be caused in any way through the use of this calculator to Sun States: Blood Banks for Animals or its creator. The entire risk as to the results and performance of this page is assumed entirely by the user. Furthermore, this dosing calculator is to be used as a guideline for transfusions. Each patient is unique and therefore, the amount of blood components transfused by a treating veterinarian is to be interpreted and administered at the sole discretion of the physician.

 

 
Send mail to rick@sunstates.org with questions or comments about this web site.
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Last modified: 06/14/08

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